Indole compounds as minimally physiologial function...

Details Indole compounds as minimally physiologial function... Indole compounds as minimally physiologial function...

A - Human Necessities

61

K

A61K 49/00 (2006.01) A61K 31/405 (2006.01) A61K 31/7056 (2006.01) A61K 41/00 (2006.01) C09B 23/08 (2006.01)

Patent

CA 2425701

Highly hydrophilic indole and benzoindole derivatives that absorb and fluoresce in the visible region of light are disclosed. These compounds are useful for physiological and organ function monitoring. Particularly, the molecules of the invention are useful for optical diagnosis of renal and cardiac diseases and for estimation of blood volume in vivo.

L'invention concerne des dérivés de benzoindole et d'indole fortement hydrophiles qui absorbent la lumière et sont fluorescents dans le spectre visible de la lumière. Ces composés sont utiles dans le contrôle des fonctions physiologique et organique. Plus précisément, les molécules selon l'invention sont utiles dans le diagnostic optique de maladies cardiaques et rénales, et dans l'estimation de la volémie in vivo.

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