C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 209/42 (2006.01)
Patent
CA 2093304
ABSTRACT OF THE DISCLOSURE An indole derivative represented by formula (I): Image (I) wherein R1 is a lower alkoxymethyl group or a formyl group, R2 is a lower alkyl group, R3 is a hydrogen atom or a lower alkyl group and R4 is a hydrogen atom or a lower alkyl group, which is useful as an intermediate for the synthesis of a compound, 5-aziridino-3-hydroxymethyl-1-methyl-2-(1H-indole-4,7- dione)prop-.beta.-ene-.alpha.-ol, which has antitumor activity.
Arai Hitoshi
Kasai Masaji
Kinugawa Masahiko
Nishikawa Hiroshi
Ogasa Takehiro
Bereskin & Parr
Kyowa Hakko Kogyo Co. Ltd.
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