Indole derivative modulators of the alpha 7 nachr

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 401/14 (2006.01) A61K 31/4427 (2006.01) A61P 25/00 (2006.01)

Patent

CA 2758772

This invention relates to modulation of the 0 nicotinic acetylcholine receptor (nAChR) by a compound of formula (I) or a salt thereof: wherein R1 is imidazolyl, pyridinyl or pyrimidinyl, any of which is optionally substituted by one group independently selected from C1-3alkyl and C1-3alkoxy.

Cette invention porte sur la modulation du récepteur nicotinique a7 de l'acétylcholine (nAChR) par un composé de formule (I) ou un sel de celui-ci : où R1 est imidazolyle, pyridinyle ou pyrimidinyle, n'importe lequel d'entre eux étant facultativement substitué par un groupe indépendamment choisi parmi alkyle en C1-3 et alcoxy en C1-3.

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