Indole derivatives

Details Indole derivatives Indole derivatives

C - Chemistry, Metallurgy

07

D

167/231, 260/277

C07D 401/04 (2006.01) A61K 31/445 (2006.01)

Patent

CA 1310968

ABSTRACT INDOLE DERIVATIVES Compounds are disclosed of formula (I) (I) Image wherein R1 represents H or C1-6 alkyl; R2 represents H or C1-6 alkyl; R3 represents H; R4 represents H or C1-3 alkyl; and pharmaceutically acceptable salts and solvates (for example hydrates) thereof. The compounds are indicated as useful for the treatment of migraine, cluster headache, chronic paroxysmal hemicrania and headache associated with vascular disorders. Processes and intermediates for their preparation and pharmaceutical compositions containing them are also disclosed.

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