C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
260/319
C07D 209/42 (2006.01)
Patent
CA 1205078
ABSTRACT INDOLE DERIVATIVES This invention relates to indole derivatives which have anti-cancer activity. According to the invention there is provided an indole derivative of the formula I:- Image in which X is an oxygen or sulphur atom, Ra is a phenyl radical which is optionally substituted by one or two groups seleted from halogen atoms; and 1-6C alkyl, 1-6C alkoxy and trifuoromethyl radicals and Rb is a hydrogen atom or a 2-6C alkoxycarbonyl radical. Manufacturing processes and pharmaceutical compositions are also described.
439878
Eakin Murdoch A.
Furr Barrington J. A.
Hayter Anthony J.
Imperial Chemical Industries Plc
Smart & Biggar
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