C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 209/12 (2006.01) A61K 31/404 (2006.01) A61P 43/00 (2006.01) C07D 403/06 (2006.01) C07D 409/06 (2006.01)
Patent
CA 2383769
The invention relates to compounds of formula (I), wherein R1 and R3 have the meaning given in Claim 1. Said compounds are potent 5-HT2A-antagonists and are suitable for the treatment of psychosis, schizophrenia, depression, neurological disorders, memory disorders, Parkinson's disease, amyotrophic lateral sclerosis, Alzheimer's disease, Huntington's disease, eating disorders, e.g. nervous bulimia and anorexia, and premenstrual syndrome and/or for positively influencing compulsive behaviours (obsessive-compulsive disorder, OCD).
Les composés de la formule (I), dans laquelle R<1> et R<3> possèdent la signification indiquée dans la revendication 1, sont des antagonistes puissants de 5-HT2A, et conviennent pour le traitement des psychoses, de la schizophrénie, des dépressions, des troubles neurologiques, des troubles de la mémoire, de la maladie de Parkinson, de la sclérose latérale amyotrophe, de la maladie d'Alzheimer, de la maladie d'Huntington, des troubles de l'alimentation tels que la boulimie ou l'anorexie nerveuse, du syndrome prémenstruel et/ou pour influer positivement sur des comportements de type obsessionnels-compulsifs (OCD).
Bartoszyk Gerd
Bottcher Henning
Greiner Hartmut
Harting Jurgen
Marz Joachim
Fetherstonhaugh & Co.
Merck Patent Gesellschaft Mit Beschraenkter Haftung
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