Indole derivatives

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 209/42 (2006.01) A61K 31/395 (2006.01) C07D 401/12 (2006.01) C07D 403/12 (2006.01) C07D 405/12 (2006.01) C07D 409/12 (2006.01) C07D 413/12 (2006.01) C07D 417/12 (2006.01) C07D 471/04 (2006.01) C07D 473/00 (2006.01) C07D 521/00 (2006.01)

Patent

CA 2199977

Indole derivatives represented by general formula (I) or pharmacologically acceptable salts thereof, wherein R1 and R2 are the same or different and each represents hydrogen, lower alkyl, -(CH2)n-OR6 or (a); R3 represents hydrogen, lower alkyl or (b); and R4 and R5 represent each hydrogen, lower alkyl, alicyclic alkyl, optionally substituted aryl, optionally substituted heterocycle, (c) or -(CH2)r-R13.

Dérivés d'indole de formule générale (I), ou sels pharmacologiquement acceptables desdits dérivés, dans laquelle R?1¿ et R?2¿ sont identiques ou différents et chacun représente hydrogène, alkyle inférieur, la formule -(CH¿2?)¿n?-OR?6¿ ou la formule (a), R?3¿ représente hydrogène, alkyle inférieur ou la formule (b) et R?4¿ et R?5¿ représentent chacun hydrogène, alkyle inférieur, alkyle alicyclique, aryle éventuellement substitué, hétérocycle éventuellement substitué, la formule (c) ou la formule -(CH¿2?)¿r?-R?13¿.

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