C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 453/02 (2006.01) A61K 31/44 (2006.01) C07D 519/00 (2006.01)
Patent
CA 2068238
Abstract 3-(Indole-2-carboxamido)quinuclidines of the formula I Ind-CO-NHR I in which Ind is a 2-indolyl group which is unsubstituted or monosubstituted to trisubstituted by alkyl, alkoxy, alkoxycarbonyl and/or alkylthio with in each case 1 - 4 C-atoms, 7-11 C-aralkyloxy, 1-5 C-acyloxy, 6-10 C-aroyloxy, 6-10 C-aryloxy, trifluoromethyl, cyano, fluorine, chlorine, hydroxyl, 1-4 C-alkyl- sulfonyloxy, 6-10 C-arylsulfonyloxy, carboxyl and/or methylenedioxy and R is 3-quinuclidinyl and their physiologically accep- table salts which show a selective serotonin- antagonistic effect and can be used as psychophar- maceuticals.
Bartoszyk Gerd
Boettcher Henning
Minck Klaus-Otto
Seyfried Christoph
Bartoszyk Gerd
Boettcher Henning
Fetherstonhaugh & Co.
Merck Patent Gesellschaft Mit Beschraenkter Haftung
Minck Klaus-Otto
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