Indole derivatives and medicinal use thereof

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 489/09 (2006.01) A61K 31/485 (2006.01) A61K 31/535 (2006.01) A61K 31/54 (2006.01) A61K 31/55 (2006.01) C07D 471/22 (2006.01) C07D 491/22 (2006.01) C07D 495/22 (2006.01) C07D 498/22 (2006.01) C07D 513/22 (2006.01)

Patent

CA 2205664

The present invention relates to indole derivatives represented by the following compound 1 and the pharmacologically acceptable acid addition salt thereof. Image The compounds of the present invention were found to exhibit strong antitussive and analgesic actions as a result of pharmacological evaluation, and can be used in the pharmaceutical field as effective antitussives and analgesics.

Dérivés d'indole typifiés par le composé <u>1</u> ou ses sels d'addition d'acide pharmacologiquement acceptables. Soumis à une évaluation pharmacologique, les composés présentent des effets antitussifs et analgésiques puissants et sont par conséquent utiles en tant que médicaments antitussifs et analgésiques.

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