Indole derivatives as beta-2 agonists

Details Indole derivatives as beta-2 agonists Indole derivatives as beta-2 agonists

C - Chemistry, Metallurgy

07

D

C07D 209/42 (2006.01) A61K 31/4045 (2006.01) A61P 11/06 (2006.01) A61P 11/08 (2006.01)

Patent

CA 2499314

The invention relates to indole derivatives of formula (1), wherein R1 to R8 and n have the meanings given in claim 1 to processes for the preparation of, intermediates used in the preparation of, compositions containing and the uses of, such derivatives. The indole derivatives according to the present invention are useful in numerous diseases, disorders and conditions, in particular inflammatory, allergic and respiratory diseases, disorders and conditions.

L'invention concerne des dérivés d'indole de formule (1) dans laquelle R¿1 ?à R¿8? et n ont la signification présentée dans la revendication 1, des procédés de préparation de ces dérivés, des intermédiaires utilisés dans la préparation de ces dérivés, des compositions renfermant ces dérivés et des utilisations de ceux-ci. Les dérivés d'indole selon l'invention sont utiles pour de nombreuses maladies, de nombreux troubles et états, notamment des maladies, troubles et états inflammatoires, allergiques et respiratoires.

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