Indole derivatives as cox ii inhibitors

Details Indole derivatives as cox ii inhibitors Indole derivatives as cox ii inhibitors

C - Chemistry, Metallurgy

07

D

C07D 209/10 (2006.01) A61K 31/404 (2006.01) A61P 29/00 (2006.01) C07D 209/30 (2006.01) C07D 209/36 (2006.01) C07D 209/42 (2006.01)

Patent

CA 2461670

This present invention relates to indole derivatives of Formula (I); wherein A, Ar and R1 to R4 are as defines in the specification. The compounds are useful as a selective COX-II inhibitor and, therefore, may be used for the treatment of COX-II mediated diseases.

Cette invention porte sur des dérivés d'indole de formula (I) dans laquelle A, Ar et R?1¿ à R?4¿ sont tels que définis dans la demande. Les composés sont utiles comme inhibiteur sélectif de COX-II et peuvent donc être utilisés dans le traitement des maladies induites par COX-II.

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