Indole derivatives as crth2 receptor antagonists

Details Indole derivatives as crth2 receptor antagonists Indole derivatives as crth2 receptor antagonists

C - Chemistry, Metallurgy

07

D

C07D 403/04 (2006.01) A61K 31/405 (2006.01) A61K 31/4192 (2006.01) A61K 31/435 (2006.01) A61P 11/06 (2006.01) C07D 471/04 (2006.01)

Patent

CA 2752981

Compound of formula (I) are antagonists of the PGD2 receptor, CRTH2, and as such are useful in the treatment and/or prevention of CRTH2-mediated diseases such as asthma.

L'invention porte sur des composés de formule (I) qui sont des antagonistes du récepteur PGD2, CRTH2, et qui, en tant que tels, sont utiles dans le traitement et/ou la prévention de maladies à médiation par CRTH2 telles que l'asthme.

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