Indole derivatives as histamine receptor antagonists

Details Indole derivatives as histamine receptor antagonists Indole derivatives as histamine receptor antagonists

C - Chemistry, Metallurgy

07

D

C07D 401/12 (2006.01) A61K 31/4439 (2006.01) A61P 3/04 (2006.01) C07D 209/42 (2006.01) C07D 401/14 (2006.01) C07D 403/12 (2006.01) C07D 403/14 (2006.01) C07D 405/14 (2006.01)

Patent

CA 2569611

The present invention relates to compounds of formula (I) wherein X, R1, R2, R3, R4 and R5 are as defined in the description and claims, and pharmaceutically acceptable salts thereof, to the preparation of such compounds and pharmaceutical compositions containing them. The compounds are useful for the treatment and/or prevention of diseases which are associated with the modulation of H3 receptors.

L'invention concerne des composés représentés par la formule (I) dans laquelle X, R?1¿, R?2¿, R?3¿, R?4¿ et R?5¿ correspondent aux définitions de la description et des revendications, ainsi que des sels pharmaceutiquement acceptables de ceux-ci, la préparation de ces composés, et des compositions pharmaceutiques contenant ces composés. Ces composés servent au traitement et/ou à la prévention des maladies associées à la modulation des récepteurs H3.

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