Indole derivatives, processes for their preparation, and...

Details Indole derivatives, processes for their preparation, and... Indole derivatives, processes for their preparation, and...

C - Chemistry, Metallurgy

07

D

260/207.1

C07D 209/28 (2006.01) C07D 405/12 (2006.01) C07D 413/12 (2006.01)

Patent

CA 1339687

The invention relates to indole derivatives of Formula (I) (see fig. I) in which X represents -COO- or -CONH- and R represents a tetrahydrofuran-2-yl, a tetrahydropyran-2-yl, an alkoxybenzyl or a straight or branched alkyl group which can optionally be substituted by a hydroxyl group, or X-R together form an oxazoline ring which can be substituted by one or more alkyl groups, with the proviso that when X is -COO- then R is other than ethyl, and their pharmaceutically acceptable salts formed with bases, and a method for their preparation. Also included in the invention are compositions containing said indoles and methods for their use as antiphlogistic agents.

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