C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 209/12 (2006.01) A61K 31/404 (2006.01)
Patent
CA 2476490
Provided is an indole long-chain alcohol represented by the following formula (I): wherein R1~, R2~, R3~ and R4~ each independently represents hydrogen atom, methyl group, acetyl group or hydroxyl group and n stands for a number from 0 to 20; and a medicament comprising the same. The compound (I) has an excellent nerve growth promoting effect, as well as antioxidative and anti- tumor effects, and thus is useful as a preventive and/or therapeutic drug for cerebral diseases such as dementia or malignant tumors such as cerebral tumor.
L'invention concerne un alcool à longue chaîne indole représenté par la formule (I), dans laquelle R1, R2, R3 et R4 représentent chacun indépendamment atome d'hydrogène, groupe méthyle, groupe acétyle ou groupe hydroxyle et n représente un nombre compris entre 0 et 20, ainsi qu'un médicament contenant celui-ci. Ce composé (I) présente un excellent effet de stimulation de la croissance du nerf, ainsi que des effets antioxydant et anti-tumoral, et est ainsi utile en tant que médicament préventif et/ou thérapeutique pour des maladies cérébrales telles que la démence ou des tumeurs malignes telles qu'une tumeur cérébrale.
Coowar Djalil
Luu Bang
Suma Yukie
Suzuki Hiroto
Yamada Masashi
Gowling Lafleur Henderson Llp
Meiji Co. Ltd.
Meiji Dairies Corporation
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