Indole derivatives, their preparation and use

C - Chemistry – Metallurgy – 07 – D

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C07D 401/12 (2006.01) A61K 31/40 (2006.01) A61K 31/445 (2006.01) A61K 31/54 (2006.01) C07D 209/48 (2006.01) C07D 209/66 (2006.01) C07D 209/70 (2006.01) C07D 209/76 (2006.01) C07D 403/12 (2006.01) C07D 417/12 (2006.01) C07D 491/18 (2006.01) C07D 495/18 (2006.01) C07D 513/18 (2006.01)

Patent

CA 2067181

2067181 9104973 PCTABS00003 Indole derivatives of formula (I) wherein R1, R2, R3 and R4 may be hydrogen or lower alkyl optionally substituted by halogen; X represents oxygen or sulfur; A1 represents a straight or branched alkylene chain containing from 2 to 4 carbon atoms; R5 is hydrogen or a straight or branched alkyl group; A2 is a straight or branched, saturated or unsaturated hydrocarbon chain containing from 2 to 6 carbon atoms; and R6 is selected from a group consisting of various structures, have been found to exhibit central nervous system activities.

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