Indole-phenylsulfonamide derivatives used as ppar-delta...

C - Chemistry – Metallurgy – 07 – D

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C07D 209/08 (2006.01) A61K 31/404 (2006.01) A61K 31/427 (2006.01) A61P 3/06 (2006.01) C07D 209/12 (2006.01) C07D 209/14 (2006.01) C07D 417/04 (2006.01)

Patent

CA 2512502

The invention relates to novel indole-phenylsulfonamide derivatives, to methods for the production thereof, and to their use in medicaments, particularly as potent PPAR-delta activating compounds, for the prevention and/or treatment of cardiovascular diseases, particularly dyslipidemias and coronary heart diseases.

L'invention concerne de nouveaux dérivés d'indol-phénylsulfonamide, des procédés permettant de les produire, ainsi que leur utilisation dans des médicaments, notamment comme composés à forte activation du récepteur PPAR-delta, pour assurer la prophylaxie et/ou le traitement d'affections cardio-vasculaires, notamment de dyslipidémies et de maladies cardiaques coronariennes.

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