Indolecarboxylic compounds and their use as pharmaceutical...

C - Chemistry – Metallurgy – 07 – D

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C07D 209/60 (2006.01) A61K 8/49 (2006.01) A61K 31/403 (2006.01) A61Q 5/00 (2006.01) C07D 209/42 (2006.01)

Patent

CA 2569685

L'invention concerne l'utilisation à titre de principe actif, dans un milieu physiologiquement acceptable, dans une composition, d'une quantité efficace d'au moins un composé de la famille des indole-carboxyliques de la formule générale (I): (voir figure I) ce composé ou ces compositions étant destinés à traiter les désordres liés à une suractivité de la 5.alpha.-réductase. Ces composés ou les compositions les contenant sont plus particulièrement destinés à traiter les désordres androgéno-dépendants comme par exemple la séborrhée et/ou l'acné et/ou l'hirsutisme et/ou l'alopécie androgénétique. L'invention concerne également de nouveaux composés de la famille des indole-carboxyliques ainsi que les compositions les contenant.

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