Indoles as modulators of nicoticic acetylcholine receptor...

Details Indoles as modulators of nicoticic acetylcholine receptor... Indoles as modulators of nicoticic acetylcholine receptor...

C - Chemistry, Metallurgy

07

D

C07D 401/12 (2006.01) A61K 31/4439 (2006.01) A61P 25/18 (2006.01)

Patent

CA 2721630

This invention relates to modulation of the .alpha.7 nicotinic acetylcholine receptor (nAChR) by a compound of List A or a salt thereof which may be represented by N-[(2-Trifluoromethyl-1H-indol-5- yl)methyl]-5-(trifluoromethyl)-2-pyrimidinecarboxamide.

L'invention concerne la modulation du récepteur a7 niconitique de l'acétylcholine (nAChR) par un composé d'une liste A ou un sel de celui-ci pouvant être representé par N-[(2-Trifluorométhyl-1H-indol-5-yl)méthyl]-5-(trifluorométhyl)-2-pyrimidinecarboxamide.

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