Indoles useful in the treatment of inflammation

Details Indoles useful in the treatment of inflammation Indoles useful in the treatment of inflammation

C - Chemistry, Metallurgy

07

D

C07D 209/42 (2006.01) A61K 31/404 (2006.01) A61P 11/00 (2006.01) A61P 29/00 (2006.01) C07D 401/04 (2006.01) C07D 401/12 (2006.01) C07D 403/04 (2006.01) C07D 405/04 (2006.01)

Patent

CA 2593155

There is provided compounds of formula (I), wherein X1, Q, T, Y, R1, R2, R3, R4 and R5 have meanings given in the description, and pharmaceutically- acceptable salts thereof, which compounds are useful in the treatment of diseases in which inhibition of the activity of a member of the MAPEG family is desired and/or required, and particularly in the treatment of inflammation.

L'invention concerne des composés selon la formule (I), dans laquelle X1, Q, T, Y, R1, R2, R3, R4 et R5 ont une signification précisée dans la description, ainsi que des sels pharmaceutiquement acceptables de ceux-ci, lesdits composés étant utiles dans le traitement de maladies dans lesquelles l'inhibition de l'activité d'un élément de la famille des MAPEG est souhaitée et/ou nécessaire, en particulier dans le traitement de l'inflammation.

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