Indoline derivative and process for producing the same

Details Indoline derivative and process for producing the same Indoline derivative and process for producing the same

C - Chemistry, Metallurgy

07

D

C07D 209/08 (2006.01)

Patent

CA 2437134

Novel intermediates represented by the following formulae (I) and (II) which are useful for synthesizing an indoline derivative having excellent ACAT inhibitory activity; and a process for producing the intermediates. (I) (II) (In the formulae, R1 represents an amino-protecting group; R2 and R3 are the same or different and each represents lower alkyl; and R4 represents hydrogen or a carboxy-protecting group.)

L'invention concerne des nouveaux produits intermédiaires représentés par les formules (I) et (II) et utilisés pour synthétiser un dérivé d'indoline présentant une excellente activité inhibitrice d'ACAT, ainsi qu'un procédé de préparation de ces produits intermédiaires. Dans les formules (I) et (II), R?1¿ représente un groupe amino-protecteur, R?2¿ et R?3¿ sont identiques ou différents et représentent chacun alkyle inférieur, et R?4¿ représente hydrogène ou un groupe carboxy-protecteur.

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