Indoline derivatives and their use as 5-ht2 receptor ligands

Details Indoline derivatives and their use as 5-ht2 receptor ligands Indoline derivatives and their use as 5-ht2 receptor ligands

C - Chemistry, Metallurgy

07

D

C07D 209/94 (2006.01) A61K 31/4045 (2006.01)

Patent

CA 2422698

The present invention relates to compounds of formula (I): (see formula I) wherein R1, R2, R3, R4, R5, R6, R7 and the ring A are as described in the description and the claims. These compounds are especially useful for the prevention and treatment of disorders of the central nervous system; damage to the central nervous system; cardiovascular disorders; gastrointestinal disorders; diabetes, sleep apnea, and especially for the treatment and prevention of obesity.

L'invention concerne des composés de formule (I): dans laquelle R<1>, R<2>, R<3>, R<4>, R<5>, R<6>, R<7> et le cycle A sont tels que décrits et revendiqués. Ces composés sont spécialement utiles dans la prévention et le traitement de troubles du système nerveux central, de dommages au système nerveux central, de troubles gastro-intestinaux, de troubles cardio-vasculaires, de diabètes, d'apnée du sommeil, et plus spécifiquement dans le traitement et la prévention de l'obésité.

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