C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 209/34 (2006.01) A61K 31/404 (2006.01) C07D 401/06 (2006.01) C07D 401/14 (2006.01) C07D 403/06 (2006.01) C07D 403/14 (2006.01) C07D 405/06 (2006.01) C07D 407/14 (2006.01) C07D 409/06 (2006.01) C07D 413/14 (2006.01)
Patent
CA 2541460
Indolinone derivatives, such as compounds of the formula (I); wherein A, m, n, R1, R 2 , R 3 , R 5 and R 6 are described herein, are disclosed herein as being useful in treating mammal having disease-states alleviated by the inhibition of PDK-1 activity.
La présente invention concerne des dérivés d'indolinone, tels que des composés représentés par la formule (I); dans cette formule, A, m, n, R?1¿, R ?2¿, R ?3¿, R ?5¿ et R ?6¿ sont tels que définis dans la description. Ces dérivés sont utiles pour traiter des mammifères présentant des états pathologiques soulagés par l'inhibition de l'activité PDK-1.
Arnaiz Damian
Bryant Judi
Chou Yuo-Ling
Feldman Richard I.
Hrvatin Paul
Marks & Clerk
Schering Aktiengesellschaft
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