C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 209/34 (2006.01) A61K 31/404 (2006.01) A61P 43/00 (2006.01) C07D 401/14 (2006.01) C07D 403/14 (2006.01)
Patent
CA 2410509
The present invention relates to certain 2-indolinone compounds which modulate the activity of protein kinases ("PKs") and phosphatases. The compounds of this invention are therefore useful in treating disorders related to abnormal PK activity. Pharmaceutical compositions comprising these compounds, methods of treating diseases utilizing pharmaceutical compositions comprising these compounds and methods of preparing them are also disclosed.
L'invention concerne certains composés 2-indolinone qui modulent l'activité de protéines kinases (PK) et de phosphatases. Ces composés sont donc utiles pour traiter des troubles se rapportant à des activités de PK anormales. L'invention concerne en outre des compositions pharmaceutiques contenant ces composés, des procédés de traitement de maladies utilisant ces compositions, ainsi que des procédés de préparation de ces compositions.
Harris G. Davis
Li Xiaoyuan
Tang Peng Cho
Osler Hoskin & Harcourt Llp
Sugen Inc.
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