Indolinone derivatives useful as protein kinase inhibitors

Details Indolinone derivatives useful as protein kinase inhibitors Indolinone derivatives useful as protein kinase inhibitors

C - Chemistry, Metallurgy

07

D

C07D 403/14 (2006.01) A61K 31/404 (2006.01) A61K 31/4166 (2006.01) A61K 31/437 (2006.01) A61P 35/00 (2006.01) C07D 207/00 (2006.01) C07D 209/00 (2006.01) C07D 241/00 (2006.01) C07D 403/06 (2006.01)

Patent

CA 2470480

Image in which R1, R2, R3 and R4 have the meanings given in the specification, are receptor tyrosine kinase inhibitors useful in the treatment of proliferative disorders, such as cancer.

L'invention concerne des composés représentés par la formule (I) dans laquelle R?1¿, R?2¿, R?3¿ et R?4¿ ont les significations données dans le descriptif. Les composés selon l'invention sont des inhibiteurs des récepteurs à tyrosine kinase utilisés dans le traitement des troubles prolifératifs, tels que le cancer.

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