Indolinones and their use as antiproliferative agents

Details Indolinones and their use as antiproliferative agents Indolinones and their use as antiproliferative agents

C - Chemistry, Metallurgy

07

D

C07D 209/34 (2006.01) A61K 31/4523 (2006.01) A61P 35/00 (2006.01) C07D 401/04 (2006.01) C07D 401/10 (2006.01) C07D 401/14 (2006.01) C07D 403/04 (2006.01) C07D 403/12 (2006.01) C07D 405/06 (2006.01) C07D 405/10 (2006.01) C07D 409/04 (2006.01) C07D 413/04 (2006.01)

Patent

CA 2589501

The invention relates to indolinone compounds of formula (I), wherein Y and R1 to R8 are defined as in claim 1, which are suitable for the treatment of diseases characterized by excessive or abnormal cell proliferation and the use thereof for preparing a pharmaceutical composition.

La présente invention concerne des dérivés d'indolinone de Formule (I), (I) R8 R1 où Y et R1 à R8 sont définis comme dans la revendication 1. Lesdits composés peuvent être employés dans le traitement de maladies caractérisées par une prolifération excessive ou anormale de cellules. La présente invention a également pour objet l'emploi desdits composés dans l'élaboration d'une préparation pharmaceutique.

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