C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 491/107 (2006.01) C07D 311/00 (2006.01) C07D 491/10 (2006.01)
Patent
CA 2410673
The present invention provides indolinospiropyran compounds and methods for their manufacture, which compounds are useful as photochromic compounds. The compounds of the invention are substituted on the indole ring with succinimide, which substitution permits ring opening of the succinimide and modulation of the bulk and photochromic properties of the compounds. The compounds may be conveniently prepared using the solid phase organic synthesis of the invention.
La présente invention concerne des composés d'indolinospiropyrane et des procédés de préparation associés, ces composés étant utiles comme composés photochromiques. Les composés selon l'invention sont substitués sur le cycle indole par du succinimide, cette substitution permettant une ouverture du cycle du succinimide et une modulation des propriétés brutes et photochromiques des composés. Ceux-ci peuvent être préparés de façon pratique au moyen de la synthèse organique à phase solide selon l'invention.
Carreira Erick M.
Zhao Weili
Essilor International (compagnie Generale D'optique)
Johnson & Johnson Vision Care Inc.
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
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