Indolizine derivatives, process of preparation and use for...

C - Chemistry – Metallurgy – 07 – D

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C07D 471/04 (2006.01)

Patent

CA 2098982

Indolizine derivatives, process of preparation and u e for the preparation of aminoalkoxybenzenesulphonyl- indolizine compounds with pharmaceutical activity. ABSTRACT The invention relates to indolizine derivatives of general formula: Image I in which: X denotes an -S or -SO2- group, each of R1 and R2, which are identical or different, denotes hydrogen, the methyl or ethyl radical or a halogen atom, R3 denotes hydrogen or a C1-C4 alkyl radical, R4 denotes a precursor radical of a carboxyl group, R denotes a C1-C6 alkyl, C1-C6 cycloalkyl or phenyl radical, and their use as intermediates for the preparation of pharmaceutically active aminoalkoxy- benzenesulphonylindolizine derivatives. Fig. Nil

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