Indolo¬2,3-a|quinolizine and indolo¬2,3-...

C - Chemistry – Metallurgy – 07 – D

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C07D 455/00 (2006.01) A61K 31/435 (2006.01) C07D 211/82 (2006.01) C07D 471/14 (2006.01) C07D 471/18 (2006.01)

Patent

CA 1248958

ABSTRACT OF THE DISCLOSURE The invention relates to new indolo[2,3-g]cyclopent[a] indolizine derivatives of the formulae (II) Image (II) and/or (III) Image (III) wherein W is alkoxycarbonyl having from one to four carbon atoms in the alkoxy moiety or cyano, R1 is hydrogen or alkyl having from one to four carbon atoms, G is a Image group, and X and Y each stands for hydrogen or together represent a C-C bond, or a pharmaceutically acceptable acid addition salt thereof, which possess valuable gastric acid secretion inhibiting activity. These compounds may be prepared by heating a compound of the formula (I) Image (I) in which Z is halo.

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