C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
167/227, 260/271
C07D 471/06 (2006.01) A61K 31/475 (2006.01)
Patent
CA 2024252
ABSTRACT OF THE DISCLOSURE Optically active compounds of formula (I): (I) Image in which R1 is hydrogen or alkyl; Xb and Yb are hydrogen or hydroxy; and Z is -NRaRb in which Ra and Rb are hydrogen, alkyl or hydroxyalkyl, or a cyclic amino group; and pharmaceutically acceptable salts thereof have enhanced anti-arrhythmic activity and may be prepared by a stereospecific synthesic process.
Fukazawa Tetsuya
Hashimoto Toshihiko
Koike Hiroyuki
Masuko Hidekazu
Mizuno Hiroshi
Marks & Clerk
Sankyo Company Limited
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