Indolomorphinan derivatives having carboxy at the 6'-position

Details Indolomorphinan derivatives having carboxy at the 6'-position Indolomorphinan derivatives having carboxy at the 6'-position

C - Chemistry, Metallurgy

07

D

C07D 489/08 (2006.01) A61K 31/485 (2006.01) A61P 1/08 (2006.01) A61P 25/04 (2006.01)

Patent

CA 2590182

A novel compound useful as a therapeutic and/or preventive agent for nausea and/or vomiting. It is a compound represented by the formula (I): (wherein R1 is hydrogen or -CHRARB (wherein RA is lower alkoxycarbonyloxy, etc. and RB is hydrogen or methyl)), a pharmaceutically acceptable salt thereof, or a solvate of either.

La présente invention concerne un nouveau composé utile en tant qu~agent thérapeutique et/ou préventif pour les nausées et/ou les vomissements. L~invention a trait à un composé représenté par la formule (I) : (dans laquelle R1 est hydrogène ou -CHRARB (où RA est alkoxycarbonyloxy inférieur, etc. et RB est hydrogène ou méthyle)), un sel pharmaceutiquement acceptable de celui-ci ou un solvate de l~un ou l~autre de ces deux éléments.

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