Indolopyridines as inhibitors of the kinesin spindle protein...

Details Indolopyridines as inhibitors of the kinesin spindle protein... Indolopyridines as inhibitors of the kinesin spindle protein...

C - Chemistry, Metallurgy

07

D

C07D 471/14 (2006.01) A61K 31/4188 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2697246

Compounds of formula (I), in which R1, R2, R3 and R4 have the meanings indicated in the description, are effective Eg5-inhibiting compounds with anti-proliferative and/or apoptosis inducing activity.

L'invention porte sur des composés représentés par la formule (I), R1, R2, R3 et R4 ayant les significations indiquées dans la description, qui sont des composés inhibiteurs de Eg5 efficaces et dotés d'une activité antiproliférative et/ou induisant l'apoptose.

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