Indoloquinazolinones

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 487/04 (2006.01) A61K 31/519 (2006.01) A61P 9/00 (2006.01) A61P 25/00 (2006.01) C07D 209/00 (2006.01) C07D 239/00 (2006.01)

Patent

CA 2415683

The invention provides compounds of formula (I) wherein R is as defined in the description, and the preparation thereof. The compounds of formula (I) are useful as pharmaceuticals, for use in the treatment of any state associated with high levels of activeted PARP.

L'invention concerne des composés de formule (I) dans laquelle R a la signification mentionnée dans la description, ainsi qu'une préparation à base desdits composés. Ces composés de formule (I) s'utilisent comme produits pharmaceutiques, dans le traitement de tout état associé à des niveaux élevés de PARP activé.

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