A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/4439 (2006.01) A61K 31/404 (2006.01) A61P 9/00 (2006.01) A61P 35/00 (2006.01) A61P 35/02 (2006.01) A61P 35/04 (2006.01)
Patent
CA 2386069
The invention relates to the use of N-substituted indol-3- glyoxylamides of general formula (I) for treating tumors, in particular, in cases of drug resistance and metastatic carcinoma, and as angiogenesis inhibitors having distinctly fewer side effects, in particular, distinctly lower neurotoxicity. The invention also relates to medicaments containing the inventive compounds.
La présente invention concerne l'utilisation d'indol-3-gloxylamides N-substitués de formule générale 1, pour le traitement de tumeurs en particulier en cas de résistance médicamenteuse et de carcinome métastatique, ainsi qu'en tant qu'inhibiteur de l'angiogénèse ayant très peu d'effets secondaires en particulier une très faible neurotoxicité. Cette invention concerne également les produits pharmaceutiques contenant ces composés.
Bacher Gerald
Beckers Thomas
Bruyneel Erik
Emig Peter
Engel Jurgen
Baxter Healthcare Sa
Marks & Clerk
Ziopharm Oncology Inc.
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