Indolyl-3 polyamines useful as antagonists of excitatory...

Details Indolyl-3 polyamines useful as antagonists of excitatory... Indolyl-3 polyamines useful as antagonists of excitatory...

C - Chemistry, Metallurgy

07

D

167/240, 260/319

C07D 209/20 (2006.01) A01N 43/38 (2006.01) A61K 31/405 (2006.01) C07D 209/18 (2006.01)

Patent

CA 2033480

This invention relates to certain polyamines found to be present in the venom of the Agelenopsis aperta spider. The polyamines of this invention and the salts thereof antagonize excitatory amino acid neurotrans- mitters, which neurotransmitters affect cells of various organisms, and are useful in antagonizing said neuro- transmitters, per se, in the treatment of excitatory amino acid neurotransmitter mediated diseases and conditions and in the control of invertebrate pests. This invention also relates to compositions comprising said polyamines and salts thereof.

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