Indolylmaleimde derivatives as pkc inhibitors

Details Indolylmaleimde derivatives as pkc inhibitors Indolylmaleimde derivatives as pkc inhibitors

C - Chemistry, Metallurgy

07

D

C07D 403/04 (2006.01) C07D 207/00 (2006.01) C07D 209/00 (2006.01) C07D 213/00 (2006.01) C07D 401/14 (2006.01)

Patent

CA 2552740

This invention relates to PKC inhibitors which are able to selectively inhibit e.g. the and optionally 0, isoforms of PKC, and their use in particular in transplantation.

L'invention se rapporte à des inhibiteurs de la protéine kinase C (PKC) qui peuvent inhiber sélectivement, par exemple, les isoformes .alpha., .beta. et éventuellement .theta. de la PKC, ainsi qu'à leur utilisation, notamment, au cours d'une transplantation.

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