Indolylpiperidine compounds, processes for the preparation...

Details Indolylpiperidine compounds, processes for the preparation... Indolylpiperidine compounds, processes for the preparation...

C - Chemistry, Metallurgy

07

D

167/231, 260/279

C07D 401/04 (2006.01) A61K 31/445 (2006.01)

Patent

CA 1336605

There is disclosed a compound of the formula: Image wherein R1 is aryl substituted with substituent(s) selected from hydroxy, protected hydroxy, halogen and lower alkoxy, A is lower alkylene, and B is lower alkenylene, and a pharmaceutically acceptable salt thereof. The preparation of this compound by a series of reactions is also disclosed as well as a pharmaceutical composition comprising the above compound and a method of therapeutic treatment of allergic diseases by administering the compound to human beings or animals. The compound is particu- larly useful for the treatment of allergic asthma, allergic rhinitis, allergic conjuctivitis, chronic urticaria, in human beings and animals.

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