Inducers of recombinant protein expression

Details Inducers of recombinant protein expression Inducers of recombinant protein expression

C - Chemistry, Metallurgy

07

K

C07K 1/06 (2006.01) C12N 5/16 (2006.01) C12N 5/06 (2006.01)

Patent

CA 2522779

The invention provides methods of increasing the production of polypeptides, optionally recombinant polypeptides, from mammalian cells using an aromatic carboxylic acid, an acetamide, and/or a hydroxamic acid compound, and cultures containing the same.

La présente invention concerne des techniques permettant d'augmenter la production de polypeptides, éventuellement de polypeptides de recombinaison, à partir de cellules de mammifère par utilisation d'acide carboxylique aromatique, d'une acétamide et/ou d'un composé acide hydroxamique et de cultures contenant ces composés.

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