Inducing cellular immune responses to p53 using peptide and...

A - Human Necessities – 61 – K

Patent

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Details

A61K 38/00 (2006.01) A61K 38/03 (2006.01) A61K 38/08 (2006.01) A61K 38/16 (2006.01) A61K 39/00 (2006.01) C07H 21/00 (2006.01) C07K 9/00 (2006.01) C07K 14/00 (2006.01) C07K 14/47 (2006.01)

Patent

CA 2393662

This invention uses our knowledge of the mechanisms by which antigen is recognized by T cells to identify and prepare p53 epitopes, and to develop epitope-based vaccines directed towards p53-bearing tumors. More specifically, this application communicates our discovery of pharmaceutical compositions and methods of use in the prevention and treatment of cancer.

La présente invention utilise nos connaissances acquises des mécanismes par lesquels les cellules T identifient l'antigène, pour identifier et préparer les épitopes p53, et élaborer des vaccins à base d'épitopes dirigés contre les tumeurs à p53. Plus particulièrement, cette invention concerne de nouvelles compositions pharmaceutiques et leurs procédés d'utilisation dans la prévention et le traitement du cancer.

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