A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 39/39 (2006.01) A61K 39/02 (2006.01) A61K 39/385 (2006.01) C07K 14/285 (2006.01)
Patent
CA 2218385
The present invention provides a method of inducing or enhancing an immune response to polysaccharides or other T cell-independent antigen by the coadministration of the antigen with bacterial lipoproteins (including covalent attachment of the antigen and lipoproteins). In a preferred embodiment, the lipoprotein of the invention is lipoprotein D.
Procédé permettant de déclencher ou de renforcer une réaction immunitaire aux polysaccharides ou à d'autres antigènes indépendants des cellules T par l'administration conjointe de l'antigène avec des lipoprotéines bactériennes (y compris avec liaison covalente de l'antigène et des lipoprotéines). Selon un mode de réalisation préféré, la lipoprotéine utilisée est la lipoprotéine D.
Capiau Carine
Hauser Pierre
Mond James J.
Prieels Jean-Paul
Snapper Clifford M.
Henry M. Jackson Foundation
Kirby Eades Gale Baker
Smithkline Beecham Biologicals S.a.
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