Induction of an antigen-specific t-lymphocyte response

Details Induction of an antigen-specific t-lymphocyte response Induction of an antigen-specific t-lymphocyte response

A - Human Necessities

61

K

A61K 35/18 (2006.01) A61K 39/395 (2006.01) G01N 33/566 (2006.01) G01N 33/68 (2006.01) C12N 5/06 (2006.01)

Patent

CA 2069541

Induction of an antigen-specific T-lymphocyte response in a T-lymphocyte culture, e.g. a primary cytotoxic T-lymphocyte(CTL) response, by loading antigen-presenting vehicles which carry empty MHC molecules with an antigen-derived T-cell-immunogenic MHC-binding peptide, culturing T-lymphocytes in the presence of the peptide-loaded antigen-presenting vehicles under specific T-lymphocyte response-inducing conditions. Optionally, an antigen-specific T-lymphocyte is isolated from the resulting culture and cultured. The process can be used for preparing CTL which are specific for viral or other foreign antigens, or CTL which are specific for autologous peptides. The process can also be used for the identification of peptides that are capable of binding to MHC and inducing a T cell response.

Affiliated with

Also associated with

Rating

Induction of an antigen-specific t-lymphocyte response does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Induction of an antigen-specific t-lymphocyte response, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Induction of an antigen-specific t-lymphocyte response will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1867243