Induction of apoptosis in cancer cells

C - Chemistry – Metallurgy – 07 – C

Patent

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Details

C07C 59/54 (2006.01) A61K 31/192 (2006.01) A61K 31/353 (2006.01) A61K 31/404 (2006.01) A61P 35/00 (2006.01) C07C 59/56 (2006.01) C07C 59/72 (2006.01) C07C 59/76 (2006.01) C07C 65/17 (2006.01) C07C 217/54 (2006.01) C07C 233/18 (2006.01) C07C 235/08 (2006.01) C07C 235/52 (2006.01) C07C 255/57 (2006.01) C07D 209/42 (2006.01) C07D 311/66 (2006.01) C07D 311/74 (2006.01) C07D 311/82 (2006.01)

Patent

CA 2468745

The present invention provides compounds that are inducers or inhibitors of apoptosis or apoptosis preceded by cell-cycle arrest. In addition, the present invention provides pharmaceutical compositions and methods for treating mammals with leukemia or other forms of cancer or for treating disease conditions caused by apoptosis of cells.

La présente invention concerne des composés induisant ou inhibant l'apoptose ou l'apoptose précédée par l'arrêt du cycle cellulaire. La présente invention concerne, de plus, des compositions pharmaceutiques et des méthodes de traitement de mammifères atteints de leucémie ou d'autres formes de cancer, ou de traitement d'états pathologiques causés par l'apoptose des cellules.

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