Induction of apoptotic or cytotoxic gene expression by...

C - Chemistry – Metallurgy – 12 – N

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Details

C12N 15/00 (2006.01) A01N 43/04 (2006.01) C07K 14/47 (2006.01) C12N 15/861 (2006.01) A61K 38/00 (2006.01) A61K 48/00 (2006.01)

Patent

CA 2322663

The present invention generally relates to viral vectors and their use as expression vectors for transforming human cells, both in vitro and in vivo. More particularly, the present invention relates to adenoviral vectors containing propapoptotic genes and their use in cancer therapy.

La présente invention concerne, de manière générale, des vecteurs viraux et leur utilisation comme vecteurs d'expression pour transformer des cellules humaines, in vitro et in vivo. En particulier, la présente invention concerne des vecteurs adénoviraux contenant des gènes propapoptotiques et leur utilisation dans les thérapies anticancéreuses.

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