Induction of ctl responses

A - Human Necessities – 61 – K

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A61K 39/00 (2006.01) C07K 14/02 (2006.01) C07K 14/025 (2006.01) C07K 14/085 (2006.01) C07K 14/11 (2006.01) C07K 14/14 (2006.01) C07K 14/16 (2006.01) C07K 14/39 (2006.01)

Patent

CA 2118026

2118026 9320840 PCTABS00027 Pharmaceutical formulations for use as immunotherapeutic or prophylactic vaccines comprise a proteinaceous particulate antigen made up of a plurality of self-assembling protein molecules. To enhance the cytotoxic T-lymphocyte (CTL) response, the formulations are adjuvant free. As adjuvant is desirable for enhancing the antibody response, a subject may be administered with two formulations, one with and one without adjuvant.

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