Induction of immune response to antigens expressed by...

A - Human Necessities – 61 – K

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Details

A61K 48/00 (2006.01) A61K 31/711 (2006.01) A61K 39/00 (2006.01) A61K 39/12 (2006.01) A61P 37/00 (2006.01) A61P 37/08 (2006.01) C12N 15/86 (2006.01)

Patent

CA 2300335

The present invention relates generally to immunization methods using recombinant viral vectors. In particular, the invention relates to methods and compositions for immunizing a subject with a nucleic acid molecule encoding an antigen of interest, wherein the nucleic acid molecule is delivered to the subject via a recombinant AAV virion.

La présente invention concerne, d'une manière générale, des méthodes d'immunisation au moyen de vecteurs viraux recombinés. En particulier, l'invention concerne des méthodes et des compositions permettant d'immuniser un sujet avec une molécule d'acide nucléique codant un antigène d'intérêt, la molécule d'acide nucléique étant administrée au sujet au moyen d'un virion AAV recombiné.

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