Induction of neurogenesis and stem cell therapy in...

Details Induction of neurogenesis and stem cell therapy in... Induction of neurogenesis and stem cell therapy in...

A - Human Necessities

61

K

A61K 31/74 (2006.01) A61K 35/14 (2006.01) A61K 38/16 (2006.01) A61K 39/385 (2006.01) A61P 25/00 (2006.01) A61P 25/28 (2006.01)

Patent

CA 2588908

A method for inducing and enhancing neurogenesis and /or oligodendrogenesis from endogenous as well as from exogenously administered stem cells comprises administering to an individual in need thereof an agent selected from the group consisting of Copolymer 1, a Copolymer 1-related polypeptide, a Copolymer 1, a Copolymer 1-related polypeptide, or a Copolymer 1-related peptide. The method is particularly useful for stem cell therapy in combination with the agent.

L'invention concerne un procédé destiné à induire et à améliorer la neurogenèse et / ou l'oligodendrogenèse provenant de cellules souches administrées de façon endogène comme de façon exogène; le procédé consiste à administrer à un individu un agent sélectionné dans le groupe constitué d'un copolymère 1, d'un polypeptide relié au copolymère 1 ou d'un peptide relié au copolymère 1, et de lymphocytes T activés par le copolymère 1, le polypeptide relié au copolymère 1 ou le peptide relié au copolymère 1. Le procédé est particulièrement utile dans la thérapie par cellules souches en combinaison avec l'agent.

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