Induction of tolerogenic phenotype in mature dendritic cells

Details Induction of tolerogenic phenotype in mature dendritic cells Induction of tolerogenic phenotype in mature dendritic cells

C - Chemistry, Metallurgy

07

K

C07K 16/28 (2006.01)

Patent

CA 2689570

The present invention relates to the use of a CD45 binding molecule to modulate the function of Dendritic cells. In particular the present invention relates to the use of a CD45 binding molecule to induce tolerogenic dendritic cells, useful in the treatment of diseases or disorders such as autoimmune diseases, transplant rejection.

La présente invention concerne l'utilisation d'un molécule liant CD45 pour moduler la fonction de cellules dendritiques. La présente invention concerne notamment l'utilisation d'un molécule liant CD45 pour induire des cellules dendritiques tolérogènes, utiles dans le traitement de maladies telles que les maladies auto-immunes et le rejet de greffe.

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