C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 9/12 (2006.01) A61K 31/7088 (2006.01) A61K 35/00 (2006.01) A61K 38/45 (2006.01) A61K 39/395 (2006.01) A61K 48/00 (2006.01) A61P 9/10 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2376630
The present invention relates to methods and compositions for therapeutic angiogenesis. More especially, this invention is directed to induction of vascular endothelial growth factor (VEGF) expression by the serine/threonine protein kinase AKT. Preferably, the compositions and methods according to the invention comprise a nucleic acid encoding AKT, and administration thereof.
La présente invention concerne des méthodes et des compositions pour angiogenèse thérapeutique. Cette invention porte plus particulièrement sur l'induction du facteur de croissance endothéliale vasculaire par la sérine/thréonine protéine kinase AKT. Les compositions et méthodes selon l'invention concernent de préférence un acide nucléique codant pour AKT et l'administration dudit acide nucléique.
Clark Kenneth
Guo Kun
Ivashchenko Yuri
Aventis Pharmaceuticals Products Inc.
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
Gencell Inc.
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