Industrial method for producing rna and system for carrying...

C - Chemistry – Metallurgy – 12 – P

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C12P 19/34 (2006.01) C12N 15/67 (2006.01) C12N 15/81 (2006.01)

Patent

CA 2532591

The invention relates to an industrial method for producing an interest heterologous RNA and to a system for carrying out said production method consisting (1) in transforming mitochondrions of yeast cells free of mitochondrial RNA with a mitochondrial transcription vector comprising at least one copy of the DNA encoding said interest heterologous RNA which are controlled by regulatory element(s) of the mitochondrial transcription and a reporter gene thereof or a fragment of said reporter gene, 2) identifying yeast transformants by incorporating the interest DNA into the mitochondrions thereof, (3) culturing the yeast mitochondrial transformants selected at the stage (2), (4) isolating the mitochondrions from the yeast mitochondrial transformants obtainable at stages (3) and in extracting and purifying the interest heterologous RNA from said mitochondrions.

Procédé de production industrielle d'un ARN hétérologue d'intérêt et système utile pour ladite production. Ledit procédé de production comprend au moins les étapes suivantes : (1) la transformation des mitochondries de cellules de levure dépourvues d'ADN mitochondrial avec un vecteur de transcription mitochondriale comprenant au moins une copie de l'ADN codant ledit ARN hétérologue d'intérêt sous le contrôle , d'élément(s) régulateur(s) de la transcription mitochondriale, et un gène rapporteur de la transformation mitochondriale ou un fragment dudit gène rapporteur, (2) l'identification des transformants de levure ayant incorporé l'ADN d'intérêt dans leurs mitochondries, (3) la culture des transformants mitochondriaux de levures sélectionnées ô l'étape (2), (4) l'isolement des mitochondries, ô partir des transformants mitochondriaux de levure obtenues ô l'étape (3) et (5) l'extraction et la purification de l'ARN hétérologue d'intérêt, ô partir desdites mitochondries.

LandOfFree

Say what you really think

Search LandOfFree.com for Canadian inventors and patents. Rate them and share your experience with other people.

Rating

Industrial method for producing rna and system for carrying... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Industrial method for producing rna and system for carrying..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Industrial method for producing rna and system for carrying... will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFCA-PAI-O-2052184

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.