Inert core implant pellet

A - Human Necessities – 61 – K

Patent

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167/165

A61K 9/22 (2006.01) A61K 9/00 (2006.01) A61K 9/16 (2006.01) A61K 31/565 (2006.01)

Patent

CA 1076480

Abstract of the Disclosure A novel sperical implant pullet which exhibits a sub- stantially constant drug release rate over a time period and substantially abrupt termination of drug release at the end of the time period is prepared which has an inert spherical core of a diameter of about 2 - 10 mm and a uniform coating of about 0.05-1 mm completely covering the core, the coating comprising about 5 - 99% suitable carrier and 1 - 95% drug. A drug may be administered at a constant rate over a chosen period by implanting the novel pellet and the release is sub- stantially abruptly terminated at the end of said period without removing the pellet. The pellet is particularly valuable for administering anabolic agents or estrus suppressing agents to animals, e.g. ruminants.

250775

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